New classification criteria for autoinflammatory periodic fevers

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OR13-004 – Evidence-based clinical classification criteria for periodic fevers

Methods All FMF, TRAPS, MKD and CAPS patients enrolled in the Eurofever registry until March 2013 were evaluated. For each disease gold standards were considered according to the following criteria: i) clinical validation by centers and disease-principal investigator, ii) confirmative molecular analysis (2 mutations for MEFV with at least one mutation in exon 10, 2 mutations of MVK gene, 1 muta...

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Perspective validation of the eurofever classification criteria for monogenic periodic fevers

Methods The provisional Eurofever classification criteria (best accuracy cut-off) were applied to patients with periodic fevers enrolled in the registry after March 2013. The following disease were analyzed: FMF, MKD, TRAPS, CAPS, PFAPA and undefined periodic fevers. Patients were divided in three subgroups: i) group A: inherited periodic fevers with genetic confirmation, ii) group B: inherited...

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PReS-FINAL-2194: Evidence-based clinical classification criteria for periodic fevers

Methods All FMF, TRAPS, MKD and CAPS patients enrolled in the Eurofever registry until March 2013 were evaluated. For each disease gold standards were considered according to the following criteria: i) clinical validation by centers and disease-principal investigator, ii) confirmative molecular analysis (2 mutations for MEFV with at least one mutation in exon 10, 2 mutations of MVK gene, 1 muta...

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How experts on autoinflammatory diseases classify inherited periodic fevers: preliminary results of the Eurofever Delphi Survey

Background Provisional evidence-based classification criteria for Familial Mediterranean Fever (FMF), Cryopyrin Associated Periodic Syndrome (CAPS), Tumor Necrosis factor Receptor Associated Periodic Syndrome (TRAPS) and Mevalonate Kinase Deficiency (MKD) have been recently developed based on data coming from the Eurofever registry. However, no consensus on how to combine clinical criteria with...

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ژورنال

عنوان ژورنال: Nature Reviews Rheumatology

سال: 2015

ISSN: 1759-4790,1759-4804

DOI: 10.1038/nrrheum.2015.15